Overview of Common Antidiabetic Drugs and Their Clinical Applications

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Diabetes affects how the body uses glucose, the main source of energy. When insulin does not work properly or is not produced in sufficient amounts, glucose builds up in the bloodstream. Over time, this can lead to serious health problems.

Modern diabetes treatment focuses not only on lowering blood sugar but also on protecting vital organs such as the heart and kidneys. DengyuePharma has summarized these medications in the following table.


Types of Diabetes Medications and Their Roles

Medication Type Common Drugs Main Function Who May Benefit Most
Metformin Metformin Improves insulin sensitivity Newly diagnosed type 2 diabetes patients
Glinides Repaglinide Controls blood sugar after meals Patients with high post-meal glucose
TZDs Pioglitazone Reduces insulin resistance Patients with insulin resistance
GLP-1 receptor agonists Liraglutide, Semaglutide Reduce appetite and blood sugar Overweight patients
SGLT2 inhibitors Empagliflozin, Dapagliflozin Remove excess glucose via urine Patients with heart or kidney disease

Benefits of Newer Diabetes Medications

Newer drug classes such as GLP-1 receptor agonists and SGLT2 inhibitors offer additional advantages beyond blood sugar control, including:

  • Weight loss or weight neutrality

  • Reduced risk of heart failure

  • Slower progression of kidney disease

These benefits make them an important part of modern diabetes care.


Conclusion

Choosing the right medication depends on many factors, including blood sugar levels, body weight, and other health conditions. Open communication with healthcare providers helps ensure the best possible outcomes.

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